The Murray Mallee Local Service Area (LSA) is a unique LSA that stretches from the pastoral districts above Renmark and Morgan in the north, the Victorian Border in the East, the Coorong in the South, and the foot hills of the Flinders Rangers in the West. The Sturt Highway and Mallee Highway are the main arterial roads in the north of the LSA, and the Dukes Highway and the Princes Highway in the south of the LSA.

The LSA is approximately 54,099 km2, and has over 66,796 residents with a strong multi-cultural component of 50 different nationalities. This area incorporates the local government areas of Renmark Paringa, Berri Barmera, Loxton Waikerie, Mid Murray, Murray Bridge, Coorong, Karoonda East Murray and Southern Mallee.

The Headquarter Station is Berri Police Station which can be found in the heart of the Berri Township, 2 ½ hours from the Adelaide CBD and 45 mins from the Victorian Border, near the River Murray. The Murray Bridge Police Station services the other major regional centre in the LSA and coordinates activities for the southern portion of the LSA.

Murray Mallee LSA has 17 police stations including nine multi member stations (Berri, Barmera, Loxton, Mannum, Meningie, Murray Bridge, Renmark Tailem Bend and Waikerie) and eight single person stations (Blanchetown, Coonalpyn, Lameroo, Karoonda, Morgan, Narrung, Pinnaroo and Swan Reach). Berri/Renmark and Murray Bridge Police provide 24/7 services to their communities and each Station has dedicated Patrols, CIB, Crime Prevention, Criminal Justice, Intelligence, Highway Patrol and Training Officer Sections.

The Murray River runs right through the area and offers many opportunities for water sports, river cruising on a houseboat, fishing and camping. The Coorong and lower lakes are also well known for fishing, boating and camping within the region.